Naloxone is a proven medicine that can reverse the effects of an opioid overdose. It is easy to use, and can be given by anyone. Having naloxone on hand is encouraged for anyone at risk of opioid overdose—or for those who know someone who may be.
Naloxone will not harm someone if opioids are not present.
Naloxone works for about 30–90 minutes; symptoms can return. Medical care will still be needed.
1. Check for Overdose Signs
Unresponsive to voice or touch
Breathing is slow, irregular, or stopped
Pinpoint pupils (very small center of the eye)
Blue or gray lips or fingernails
Snoring, gurgling, or choking sounds
2. Call 911 & Try to Wake the Person
Call 911 immediately. Keep the phone on speaker if possible.
Lay the person flat on their back.
Shout their name, shake shoulders, and rub firmly on the center of the chest (sternum).
3. Give the First Dose
Peel back the package tab with the circle to remove the device.
Do not test the spray. Use only when ready to give the dose.
Hold with your thumb on the bottom plunger and two fingers on the sides of the nozzle.
Tilt the head back and support the neck with your hand.
Insert the tip into one nostril until your fingers touch the bottom of the nose.
Press the plunger firmly to give the full dose, then remove the device.
4. Support Breathing & Monitor
Turn the person on their side (recovery position).
Watch breathing closely.
Always stay with the person until emergency responders arrive.
5. Repeat if Needed
If no response or normal breathing in 2–3 minutes, give a new dose in the other nostril.
Repeat every 2–3 minutes with new devices until the person responds or help arrives.